The Multiplicative Instrumental Variable Model
Jiewen Liu, Chan Park, Yonghoon Lee, Yunshu Zhang, Mengxin Yu, James M. Robins, Eric J. Tchetgen Tchetgen

TL;DR
This paper introduces the Multiplicative Instrumental Variable Model (MIV), a new approach that relaxes traditional IV assumptions by encoding no multiplicative interaction, enabling nonparametric identification of treatment effects.
Contribution
The MIV model formalizes a novel independence condition based on no multiplicative interaction, allowing for identification of treatment effects without homogeneity assumptions.
Findings
MIV provides nonparametric identification of ATT via a Wald ratio estimator.
Proposed estimators are multiply robust and semiparametric efficient.
Simulations and real data illustrate the effectiveness of the MIV approach.
Abstract
The instrumental variable (IV) design is a common approach to address hidden confounding bias. For validity, an IV must impact the outcome only through its association with the treatment. In addition, IV identification has required a homogeneity condition such as monotonicity or no unmeasured common effect modifier between the additive effect of the treatment on the outcome, and that of the IV on the treatment. In this work, we introduce the Multiplicative Instrumental Variable Model (MIV), which encodes a condition of no multiplicative interaction between the instrument and an unmeasured confounder in the treatment propensity score model. Thus, the MIV provides a novel formalization of the core IV independence condition interpreted as independent mechanisms of action, by which the instrument and hidden confounders influence treatment uptake, respectively. As we formally establish, MIV…
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