Method: Using generalized additive models in the livestock animal sciences

TL;DR

This paper introduces generalized additive models (GAMs) as a flexible method for modeling nonlinear relationships in animal science data, demonstrating their utility through practical examples and R code.

Contribution

It provides a clear overview of GAMs, illustrating their application in animal science with examples, and highlights their advantages over traditional parametric models.

Findings

GAMs offer better data fit than parametric models in examples.

Hierarchical GAMs can estimate growth across multiple animals.

GAMs facilitate formal statistical inference in experimental designs.

Abstract

Nonlinear relationships between covariates and a response variable of interest are frequently encountered in animal science research. Within statistical models, these nonlinear effects have, traditionally, been handled using a range of approaches including transformation of the response, parametric nonlinear models based on theory or phenomenological grounds, or through fixed degree spline or polynomial terms. If it is desirable to learn the shape of these relationships then generalized additive models (GAMs) are an excellent alternative. GAMs extend the generalized linear model such that the linear predictor includes one or more smooth functions, parameterised using penalised splines. A wiggliness penalty on each function is used to avoid over fitting while estimating the parameters of the spline basis functions to maximise fit to the data. Modern GAMs include automatic smoothness selection methods to find an optimal balance between fit and complexity of the estimated functions. Because GAMs learn the shapes of functions from the data, the user can avoid forcing a particular model to their data. Here, I provide a brief description of GAMs and visually illustrate how they work. I then demonstrate the utility of GAMs on three example data sets of increasing complexity, to show i) how learning from data can produce a better fit to data than that of parametric models, ii) how hierarchical GAMs can be used to estimate growth data from multiple animals in a single model, and iii) how hierarchical GAMs can be used for formal statistical inference in a designed experiment. The examples are supported by R code that demonstrates how to fit each of the models considered, and reproduces the results of the statistical analyses reported here. Ultimately, I show that GAMs are a modern, flexible, and highly usable statistical model that is amenable to many research problems in animal science.