AI-VaxGuide: An Agentic RAG-Based LLM for Vaccination Decisions
Abdellah Zeggai, Ilyes Traikia, Abdelhak Lakehal, and Abdennour Boulesnane

TL;DR
AI-VaxGuide is a multilingual, agentic RAG-based system that provides accurate, context-aware answers to vaccination questions, improving access to complex immunization guidelines for healthcare professionals in real-time.
Contribution
The paper introduces an innovative agentic RAG framework for medical QA, enhancing vaccination information retrieval with multi-step reasoning and real-time mobile deployment.
Findings
Outperforms traditional QA methods in complex medical queries
Effective in multilingual and multi-step vaccination questions
Deployed successfully in a mobile app for clinical use
Abstract
Vaccination plays a vital role in global public health, yet healthcare professionals often struggle to access immunization guidelines quickly and efficiently. National protocols and WHO recommendations are typically extensive and complex, making it difficult to extract precise information, especially during urgent situations. This project tackles that issue by developing a multilingual, intelligent question-answering system that transforms static vaccination guidelines into an interactive and user-friendly knowledge base. Built on a Retrieval-Augmented Generation (RAG) framework and enhanced with agent-based reasoning (Agentic RAG), the system provides accurate, context-sensitive answers to complex medical queries. Evaluation shows that Agentic RAG outperforms traditional methods, particularly in addressing multi-step or ambiguous questions. To support clinical use, the system is…
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