Recent advances in DNA origami-engineered nanomaterials and applications

TL;DR

This review highlights recent progress in DNA origami-engineered nanomaterials over the past five years, emphasizing innovative concepts, methodologies, and potential applications across multiple scientific disciplines.

Contribution

It provides a comprehensive overview of recent advances and unexplored research directions in DNA origami nanomaterials, fostering interdisciplinary innovation.

Findings

Significant developments in DNA origami techniques

Emerging applications in nanomaterials and biomedicine

Identification of future research avenues

Abstract

DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics, engineering, and materials science can elegantly converge. Since the original proposal of Nadrian Seeman, significant advances have been achieved in the past four decades. During this glory time, the DNA origami technique developed by Paul Rothemund further pushed the field forward with a vigorous momentum, fostering a plethora of concepts, models, methodologies, and applications that were not thought of before. This review focuses on the recent progress in DNA origami-engineered nanomaterials in the past five years, outlining the exciting achievements as well as the unexplored research avenues. We believe that the spirits and asset that Seeman left for scientists will continue to bring inter-disciplinary innovations and useful applications to this field in the next decade.