On Efficient Estimation of Distributional Treatment Effects under Covariate-Adaptive Randomization
Undral Byambadalai, Tomu Hirata, Tatsushi Oka, Shota Yasui

TL;DR
This paper introduces a flexible, machine learning-based framework for estimating distributional treatment effects in covariate-adaptive randomized experiments, achieving optimal efficiency and improved inference.
Contribution
It develops a distribution regression approach that incorporates additional covariates, attains the semiparametric efficiency bound, and provides valid inference methods under covariate-adaptive randomization.
Findings
Estimator attains the semiparametric efficiency bound.
Simulation studies show improved estimation accuracy.
Empirical analysis demonstrates practical benefits in microcredit data.
Abstract
This paper focuses on the estimation of distributional treatment effects in randomized experiments that use covariate-adaptive randomization (CAR). These include designs such as Efron's biased-coin design and stratified block randomization, where participants are first grouped into strata based on baseline covariates and assigned treatments within each stratum to ensure balance across groups. In practice, datasets often contain additional covariates beyond the strata indicators. We propose a flexible distribution regression framework that leverages off-the-shelf machine learning methods to incorporate these additional covariates, enhancing the precision of distributional treatment effect estimates. We establish the asymptotic distribution of the proposed estimator and introduce a valid inference procedure. Furthermore, we derive the semiparametric efficiency bound for distributional…
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Taxonomy
TopicsAdvanced Causal Inference Techniques · Statistical Methods and Inference · Statistical Methods in Clinical Trials
