A Step towards Interpretable Multimodal AI Models with MultiFIX
Mafalda Malafaia, Thalea Schlender, Tanja Alderliesten, Peter A. N. Bosman

TL;DR
MultiFIX is a novel multimodal data fusion pipeline that enhances interpretability by explicitly engineering features from different modalities and replacing black-box components with explainable models, ensuring trustworthy AI in critical domains.
Contribution
The paper introduces MultiFIX, a new approach that combines deep learning with interpretable models for multimodal data fusion, improving transparency without sacrificing accuracy.
Findings
MultiFIX effectively explains feature contributions across modalities.
The approach maintains high predictive performance while enhancing interpretability.
Experiments on synthetic datasets validate the method's ability to explain multimodal interactions.
Abstract
Real-world problems are often dependent on multiple data modalities, making multimodal fusion essential for leveraging diverse information sources. In high-stakes domains, such as in healthcare, understanding how each modality contributes to the prediction is critical to ensure trustworthy and interpretable AI models. We present MultiFIX, an interpretability-driven multimodal data fusion pipeline that explicitly engineers distinct features from different modalities and combines them to make the final prediction. Initially, only deep learning components are used to train a model from data. The black-box (deep learning) components are subsequently either explained using post-hoc methods such as Grad-CAM for images or fully replaced by interpretable blocks, namely symbolic expressions for tabular data, resulting in an explainable model. We study the use of MultiFIX using several training…
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Taxonomy
TopicsExplainable Artificial Intelligence (XAI) · Adversarial Robustness in Machine Learning · Machine Learning in Healthcare
