Mind the Gap: Bridging the Divide Between AI Aspirations and the Reality of Autonomous Characterization
Grace Guinan, Addison Salvador, Michelle A. Smeaton, Andrew Glaws, Hilary Egan, Brian C. Wyatt, Babak Anasori, Kevin R. Fiedler, Matthew J. Olszta, and Steven R. Spurgeon

TL;DR
This paper discusses advancements in autonomous electron microscopy characterization, emphasizing domain-aware multimodal models and addressing practical challenges to realize AI-driven materials analysis in real-world settings.
Contribution
It introduces recent developments in domain-aware multimodal models for microscopy and analyzes the gap between theoretical potential and practical implementation.
Findings
Successful development of domain-aware multimodal models
Identification of key challenges for real-world autonomous microscopy
Highlighting necessary future developments
Abstract
What does materials science look like in the "Age of Artificial Intelligence?" Each materials domain-synthesis, characterization, and modeling-has a different answer to this question, motivated by unique challenges and constraints. This work focuses on the tremendous potential of autonomous characterization within electron microscopy. We present our recent advancements in developing domain-aware, multimodal models for microscopy analysis capable of describing complex atomic systems. We then address the critical gap between the theoretical promise of autonomous microscopy and its current practical limitations, showcasing recent successes while highlighting the necessary developments to achieve robust, real-world autonomy.
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