Epilepsy and its driving forces: understanding the forces behind epileptical pathogenisis

TL;DR

This review explores the historical, mechanistic, and etiological aspects of epilepsy, aiming to inform personalized treatments and public health strategies for this complex neurological disorder.

Contribution

It provides a comprehensive overview of epileptogenesis mechanisms, causes, and current diagnostic and treatment approaches, highlighting areas for future research and personalized therapy.

Findings

Categorization of epileptogenesis mechanisms

Overview of diagnostic and treatment strategies

Identification of challenges in defining epilepsy

Abstract

Epilepsy is a neurological disorder characterized by seizures and epileptic events intertwined with religious and personal beliefs since prehistoric times. This review paper explores the historical context and challenges in defining epilepsy. The formal definition was established twenty years ago, and the multifaceted causes of this neurological disorder. It aims to pave the way for personalised therapeutic strategies, research advancements, and informed public health planning to enhance the lives of those affected by this complex neurological condition. In addition, this review paper focuses on the mechanisms and etiologies of epileptogenesis, categorizing them by mechanisms and the underlying causes of the disorder. The review paper provides a brief overview of the current state of the art in the diagnosis, diagnosis, treatment, and treatment of epileptiform seizures.