Treatment Effect Estimation for Graph-Structured Targets
Shonosuke Harada, Ryosuke Yoneda, Hisashi Kashima

TL;DR
This paper introduces GraphTEE, a novel framework for estimating treatment effects on graph-structured targets, effectively mitigating observational bias by focusing on confounding variables and providing theoretical bias reduction analysis.
Contribution
The study proposes GraphTEE, a new method tailored for treatment effect estimation on graph-structured data, with a focus on bias mitigation and confounding variable consideration.
Findings
GraphTEE outperforms baseline methods in synthetic datasets.
Theoretical analysis confirms improved bias mitigation.
Experimental results demonstrate effectiveness on semi-synthetic data.
Abstract
Treatment effect estimation, which helps understand the causality between treatment and outcome variable, is a central task in decision-making across various domains. While most studies focus on treatment effect estimation on individual targets, in specific contexts, there is a necessity to comprehend the treatment effect on a group of targets, especially those that have relationships represented as a graph structure between them. In such cases, the focus of treatment assignment is prone to depend on a particular node of the graph, such as the one with the highest degree, thus resulting in an observational bias from a small part of the entire graph. Whereas a bias tends to be caused by the small part, straightforward extensions of previous studies cannot provide efficient bias mitigation owing to the use of the entire graph information. In this study, we propose Graph-target Treatment…
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Taxonomy
TopicsComputational Drug Discovery Methods · Machine Learning in Materials Science
MethodsFocus
