New Graphs at the braingraph.org Website for Studying the Aging Brain Circuitry

TL;DR

This paper introduces new human brain connectome datasets for studying aging and Alzheimer's disease, derived from diffusion MRI data and made available on the braingraph.org website, enhancing resources for neuroscience research.

Contribution

The paper reports the addition of connectomes from healthy and demented subjects aged 42-95 to the braingraph.org database, based on the OASIS-3 dataset processed with Connectome Mapper Toolkit v.3.1.

Findings

New connectome datasets for aging and Alzheimer's disease.

Resource for studying structural brain changes across lifespan.

Potential to facilitate research on aging-related brain circuitry.

Abstract

Human braingraphs or connectomes are widely studied in the last decade to understand the structural and functional properties of our brain. In the last several years our research group has computed and deposited thousands of human braingraphs to the braingraph.org site, by applying public structural (diffusion) MRI data from young and healthy subjects. Here we describe a recent addition to the {\tt braingraph.org} site, which contains connectomes from healthy and demented subjects between 42 and 95 years of age, based on the public release of the OASIS-3 dataset. The diffusion MRI data was processed with the Connectome Mapper Toolkit v.3.1. We believe that the new addition to the braingraph.org site will become a useful resource for enlightening the aging circuitry of the human brain in healthy and diseased subjects, including those with Alzheimer's disease in several stages.