Toward a Unified Graph-Based Representation of Medical Data for Precision Oncology Medicine
Davide Belluomo, Tiziana Calamoneri, Giacomo Paesani, Ivano, Salvo

TL;DR
This paper introduces a unified graph-based model that integrates genetic data and medical records into a knowledge graph, enabling enhanced insights and explanations in precision oncology medicine.
Contribution
It proposes a novel unified graph representation combining diverse medical data sources into a knowledge graph for improved oncology insights.
Findings
Enhanced understanding of oncology through integrated data
Reduction of medical tasks to known computational problems
Efficient algorithms applied to medical data analysis
Abstract
We present a new unified graph-based representation of medical data, combining genetic information and medical records of patients with medical knowledge via a unique knowledge graph. This approach allows us to infer meaningful information and explanations that would be unavailable by looking at each data set separately. The systematic use of different databases, managed throughout the built knowledge graph, gives new insights toward a better understanding of oncology medicine. Indeed, we reduce some useful medical tasks to well-known problems in theoretical computer science for which efficient algorithms exist.
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Taxonomy
TopicsBioinformatics and Genomic Networks · Biomedical Text Mining and Ontologies · Gene expression and cancer classification
MethodsSparse Evolutionary Training
