Llettuce: An Open Source Natural Language Processing Tool for the Translation of Medical Terms into Uniform Clinical Encoding
James Mitchell-White, Reza Omdivar, Benjamin Partridge, Esmond Urwin, Karthikeyan Sivakumar, Ruizhe Li, Andy Rae, Xiaoyan Wang, Theresia Mina, Tom Giles, Diego Garcia-Gil, Tim Beck, John Chambers, Grazziela Figueredo, and Philip R Quinlan

TL;DR
Llettuce is an open-source NLP tool that automates the translation of medical terms into standardized clinical codes using advanced language models, improving accuracy and privacy compliance over existing solutions.
Contribution
It introduces a novel NLP-based approach with large language models and fuzzy matching for medical term mapping, emphasizing local deployment and GDPR compliance.
Findings
Enhanced accuracy in medical term mapping.
Supports local deployment for data privacy.
Outperforms traditional methods in semantic nuance handling.
Abstract
This paper introduces Llettuce, an open-source tool designed to address the complexities of converting medical terms into OMOP standard concepts. Unlike existing solutions such as the Athena database search and Usagi, which struggle with semantic nuances and require substantial manual input, Llettuce leverages advanced natural language processing, including large language models and fuzzy matching, to automate and enhance the mapping process. Developed with a focus on GDPR compliance, Llettuce can be deployed locally, ensuring data protection while maintaining high performance in converting informal medical terms to standardised concepts.
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Taxonomy
TopicsBiomedical Text Mining and Ontologies · Natural Language Processing Techniques · linguistics and terminology studies
