A kinetic chemotaxis model and its diffusion limit in slab geometry
Herbert Egger, Kathrin Hellmuth, Nora Philippi, Matthias Schlottbom

TL;DR
This paper develops a kinetic model for chemotaxis in slab geometry, proves local existence and uniqueness of solutions, and demonstrates their convergence to a Keller-Segel diffusion model with explicit rates.
Contribution
It introduces a kinetic chemotaxis model in slab geometry and rigorously establishes its diffusion limit to the Keller-Segel model, including convergence rates.
Findings
Proved local existence and uniqueness of solutions.
Established convergence to Keller-Segel model in the high tumbling rate limit.
Derived explicit convergence rates under regularity assumptions.
Abstract
Chemotaxis describes the intricate interplay of cellular motion in response to a chemical signal. We here consider the case of slab geometry which models chemotactic motion between two infinite membranes. Like previous works, we are particularly interested in the asymptotic regime of high tumbling rates. We establish local existence and uniqueness of solutions to the kinetic equation and show their convergence towards solutions of a parabolic Keller-Segel model in the asymptotic limit. In addition, we prove convergence rates with respect to the asymptotic parameter under additional regularity assumptions on the problem data. Particular difficulties in our analysis are caused by vanishing velocities in the kinetic model as well as the occurrence of boundary terms.
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMathematical Biology Tumor Growth · MRI in cancer diagnosis · Radiomics and Machine Learning in Medical Imaging
