Volume-preserving mean-curvature flow as a singular limit of a diffusion-aggregation equation
Antoine Mellet, Michael Rozowski

TL;DR
This paper demonstrates that in a specific chemotaxis model, the interface between high and low density regions evolves according to a volume-preserving mean-curvature flow, linking phase separation to geometric flow limits.
Contribution
It establishes that the phase separation in the elliptic-parabolic PKS model asymptotically follows a volume-preserving mean-curvature flow, extending previous results from the Hele-Shaw problem.
Findings
Phase separation occurs in the elliptic-parabolic PKS model.
The interface evolution converges to a volume-preserving mean-curvature flow.
The result connects chemotaxis models to geometric flow limits.
Abstract
The Patlak-Keller-Segel system of equations (PKS) is a classical example of aggregation-diffusion equation in which the repulsive effect of diffusion is in competition with the attractive chemotaxis term. Recent work on the Parabolic-Elliptic PKS model have shown that when the repulsion is modeled by a nonlinear diffusion term with , this competition leads to phase separation phenomena. Furthermore, in some asymptotic regime corresponding to a large population observed over a long enough time, the interface separating regions of high and low density evolves according to the Hele-Shaw free boundary problem with surface tension. In the present paper, we consider the counterpart of that model, namely the Elliptic-Parabolic PKS model and we prove that the same phase separation phenomena occurs, but the motion of the interface is now described (asymptotically)…
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Taxonomy
TopicsMathematical Biology Tumor Growth · advanced mathematical theories · Stochastic processes and statistical mechanics
