Photonic biosensing via Su-Schrieffer-Heeger boundary modes

TL;DR

This paper introduces a robust photonic biosensor utilizing Su-Schrieffer-Heeger boundary modes for multiplexed detection of disease markers, enabling single-shot measurements with high reliability in nanophotonic systems.

Contribution

The paper presents a novel photonic crystal biosensor design based on Su-Schrieffer-Heeger boundary modes that can detect multiple disease markers simultaneously with enhanced robustness.

Findings

Detects three disease markers in a single measurement

Demonstrates robustness against defects and disorders

Enables recognition of various marker combinations

Abstract

We propose a conceptual device for multiplexed biosensor in a photonic crystal chip based on the Su-Schrieffer-Heeger mechanism. Remarkably, the proposed biosensor can identify three distinct disease markers through a single-shot photon transmission measurement, due to the couplings among the three Su-Schrieffer-Heeger boundary modes in the photonic crystal. Our biosensor design is more robust against defects and disorders inevitable in real-life device applications than previous designs. Such robustness is invaluable for achieving efficient, reliable, and integrated biosensing based on nanophotonic systems. We further demonstrate that various combinations of disease markers can be recognized via the photon transmission spectrum, unveiling a promising route toward high performance advanced biosensing for future biomedical technology.