ProS2Vi: a Python Tool for Visualizing Proteins Secondary Structure

TL;DR

ProS2Vi is a Python tool that provides an intuitive, customizable, and secure way to visualize protein secondary structures with export options, improving accessibility and analysis of protein data.

Contribution

ProS2Vi introduces a modern, user-friendly Python-based visualization tool for protein secondary structures with customizable features and secure local operation.

Findings

Enhanced visualization with customizable options.

Supports exporting visualizations as PDFs.

Operates securely on local machines.

Abstract

The Protein Secondary Structure Visualizer ProS2Vi is a novel Python-based visualization tool designed to enhance the analysis and accessibility of protein secondary structures calculated and identified by the Dictionary of Secondary Structure of Proteins algorithm. Leveraging robust Python libraries such as Biopython for data handling, Flask, for Graphical User Interface, Jinja2, and wkhtmltopdf for visualization, ProS2Vi offers a modern and intuitive representation for visualization of the DSSP assigned secondary structures to each residue of any proteins amino acid sequence. Significant features of ProS2Vi include customizable icon colors, the number of residues per line, and the ability to export visualizations as scalable PDFs, enhancing both visual appeal and functional versatility through a user-friendly GUI. We have designed ProS2Vi specifically for secure and local operation, which significantly increases security when dealing with novel protein data.