On the Number of Observation Nodes in Boolean Networks

TL;DR

This paper investigates the bounds on the number of observation nodes needed for different types of Boolean networks to be observable, providing new theoretical limits using entropy, counting, and combinatorial methods.

Contribution

It introduces novel techniques to derive lower and upper bounds on observation nodes for various Boolean network models, filling a gap in the existing literature.

Findings

Lower bounds depend on network type and are derived using entropy and counting methods.

Upper bounds are established through combinatorial analysis for different network classes.

The bounds provide practical guidelines for designing observable Boolean networks.

Abstract

A Boolean network (BN) is called observable if any initial state can be uniquely determined from the output sequence. In the existing literature on observability of BNs, there is almost no research on the relationship between the number of observation nodes and the observability of BNs, which is an important and practical issue. In this paper, we mainly focus on three types of BNs with $n$ nodes (i.e., $K$-AND-OR-BNs, $K$-XOR-BNs, and $K$-NC-BNs, where $K$ is the number of input nodes for each node and NC means nested canalyzing) and study the upper and lower bounds of the number of observation nodes for these BNs. First, we develop a novel technique using information entropy to derive a general lower bound of the number of observation nodes, and conclude that the number of observation nodes cannot be smaller than $\left[(1-K)+\frac{2^{K}-1}{2^{K}}\log_{2}(2^{K}-1)\right]n$ to ensure that any $K$-AND-OR-BN is observable, and similarly, some lower bound is also obtained for $K$-NC-BNs. Then for any type of BN, we also develop two new techniques to infer the general lower bounds, using counting identical states at time 1 and counting the number of fixed points, respectively. On the other hand, we derive nontrivial upper bounds of the number of observation nodes by combinatorial analysis of several types of BNs. Specifically, we indicate that $\left(\frac{2^{K}-K-1}{2^{K}-1}\right)n,~1$, and $\lceil \frac{n}{K}\rceil$ are the best case upper bounds for $K$-AND-OR-BNs, $K$-XOR-BNs, and $K$-NC-BN, respectively.