Characterization of a Biosensor Based on Graphene Field Effect Transistors for Body Fluid Analytes: Channel Resistance

TL;DR

This study preliminarily characterizes the resistance behavior of graphene FET biosensors in biological fluids, highlighting their potential for analyte detection through electrical response changes.

Contribution

It provides initial resistance measurements of commercial GFETs with dry and wet gates, offering foundational data for biosensor development.

Findings

Channel resistance increases with wet gate conditions.

Ohmic response is linear across the tested voltage range.

Recommendations for further research are proposed.

Abstract

Field-Effect Transistors with graphene channels or GFETs are an interesting alternative for the detection of analytes in biological fluids since the electrical behavior of the channel changes when exposed to a sample (among other detection strategies). In this work a preliminary characterization is made in terms of the resistance of the channel for a commercial device that has GFETs of 1 and 3 channels for cases of dry and wet gate at atmospheric pressure. The channel resistance was obtained by sweeping the drain-source voltage from -1 to +1V and measuring the drain current in a test station developed for this purpose, for gate cases with and without a PBS 0.001X reference solution. The ohmic response of the channel is linear current with respect to voltage, being greater resistance in the case of wet gate. An increase in resistance with respect to voltage was observed that it is important to review. It was possible to make the ohmic characterization of the channel and a series of recommendations are suggested to continue this research.