12 Labours tools for developing Functional Tissue Units
Jagir R. Hussan
TL;DR
This paper introduces a technical approach and tools for modeling Functional Tissue Units (FTUs) as interconnected cell systems using port-Hamiltonian or DAE frameworks, with a Python library and web interface.
Contribution
It presents a novel modeling framework and software tools for constructing and simulating FTUs based on cellular dynamics and interconnections.
Findings
Development of a Python library for FTU modeling
Browser-based tool for composing FTU graphs
Demonstration of the approach's applicability
Abstract
A brief introduction of the technical approach to model FTUs as an aggregate of cells, whose state transition dynamics are mathematically represented as port-hamiltonians or Differential Algebraic equations is presented. A python library and browser based tool to enable modellers to compose the FTU graph, specify the cellular equations and the interconnection between the cells at the level of physical quantities they exchange consistent with the technical approach is discussed.
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Taxonomy
TopicsBiomedical Ethics and Regulation
MethodsLib