Laboratory-Scale AI: Open-Weight Models are Competitive with ChatGPT Even in Low-Resource Settings
Robert Wolfe, Isaac Slaughter, Bin Han, Bingbing Wen, Yiwei Yang,, Lucas Rosenblatt, Bernease Herman, Eva Brown, Zening Qu, Nic Weber, Bill Howe

TL;DR
This paper demonstrates that small, open-weight AI models can perform competitively with large proprietary models like ChatGPT in low-resource and domain-specific settings, emphasizing transparency and cost-effectiveness.
Contribution
It provides a comprehensive evaluation showing open-weight models can match high-end models in performance, bias, and privacy in resource-constrained environments, highlighting their practical viability.
Findings
Open models achieve competitive performance with minimal fine-tuning.
Open models offer advantages in bias mitigation and privacy.
Cost and resource requirements are significantly lower for open models.
Abstract
The rapid proliferation of generative AI has raised questions about the competitiveness of lower-parameter, locally tunable, open-weight models relative to high-parameter, API-guarded, closed-weight models in terms of performance, domain adaptation, cost, and generalization. Centering under-resourced yet risk-intolerant settings in government, research, and healthcare, we see for-profit closed-weight models as incompatible with requirements for transparency, privacy, adaptability, and standards of evidence. Yet the performance penalty in using open-weight models, especially in low-data and low-resource settings, is unclear. We assess the feasibility of using smaller, open-weight models to replace GPT-4-Turbo in zero-shot, few-shot, and fine-tuned regimes, assuming access to only a single, low-cost GPU. We assess value-sensitive issues around bias, privacy, and abstention on three…
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