DrHouse: An LLM-empowered Diagnostic Reasoning System through Harnessing Outcomes from Sensor Data and Expert Knowledge

TL;DR

DrHouse is an innovative LLM-based virtual doctor system that integrates sensor data, continuously updated medical databases, and a novel diagnostic algorithm to improve accuracy and user acceptance in digital healthcare.

Contribution

It introduces a multi-turn consultation system that combines sensor data, dynamic medical knowledge, and a new diagnostic algorithm for enhanced medical diagnosis.

Findings

Up to 18.8% increase in diagnosis accuracy over baselines

75% medical experts and 91.7% patients willing to use DrHouse

Effective multi-turn diagnostic refinement

Abstract

Large language models (LLMs) have the potential to transform digital healthcare, as evidenced by recent advances in LLM-based virtual doctors. However, current approaches rely on patient's subjective descriptions of symptoms, causing increased misdiagnosis. Recognizing the value of daily data from smart devices, we introduce a novel LLM-based multi-turn consultation virtual doctor system, DrHouse, which incorporates three significant contributions: 1) It utilizes sensor data from smart devices in the diagnosis process, enhancing accuracy and reliability. 2) DrHouse leverages continuously updating medical databases such as Up-to-Date and PubMed to ensure our model remains at diagnostic standard's forefront. 3) DrHouse introduces a novel diagnostic algorithm that concurrently evaluates potential diseases and their likelihood, facilitating more nuanced and informed medical assessments. Through multi-turn interactions, DrHouse determines the next steps, such as accessing daily data from smart devices or requesting in-lab tests, and progressively refines its diagnoses. Evaluations on three public datasets and our self-collected datasets show that DrHouse can achieve up to an 18.8% increase in diagnosis accuracy over the state-of-the-art baselines. The results of a 32-participant user study show that 75% medical experts and 91.7% patients are willing to use DrHouse.