Two-dimensional signal-dependent parabolic-elliptic Keller-Segel system and its mean-field derivation
Lukas Bol, Li Chen, Yue Li

TL;DR
This paper establishes the well-posedness and mean-field derivation of a two-dimensional signal-dependent Keller-Segel system, addressing mathematical challenges like degeneracy and aggregation effects on the whole space.
Contribution
It introduces a novel entropy estimate and proves the rigorous mean-field limit for the system with a mollified interaction potential.
Findings
Established well-posedness of the system.
Proved convergence of particle trajectories in expectation.
Derived higher regularity and strong L^1 convergence under initial data assumptions.
Abstract
In this paper, the well-posedness of two-dimensional signal-dependent Keller-Segel system and its mean-field derivation from a interacting particle system on the whole space are investigated. The signal dependence effect is reflected by the fact that the diffusion coefficient in the particle system depends non-linearly on the interactions between the individuals. Therefore, the mathematical challenge in studying the well-posedness of this system lies in the possible degeneracy and the aggregation effect when the concentration of signal becomes unbounded. The well-established method on bounded domains, to obtain the appropriate estimates for the signal concentration, is invalid for the whole space case. Motivated by the entropy minimization method and Onofri's inequality, which has been successfully applied for the parabolic-parabolic Keller-Segel system, we establish a complete entropy…
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Taxonomy
TopicsMathematical Biology Tumor Growth · MRI in cancer diagnosis · advanced mathematical theories
