Grounding Realizable Entities
Michael Rabenberg, Carter Benson, Federico Donato, Yongqun He, Anthony, Huffman, Shane Babcock, John Beverley

TL;DR
This paper refines ontological representations of qualities, dispositions, and roles within Basic Formal Ontology, proposing new grounding relations to better capture subtle distinctions in life science research, exemplified by host-pathogen interactions.
Contribution
It introduces new grounding relations between qualities, dispositions, and roles to address gaps in BFO's existing framework, enhancing ontological modeling.
Findings
Proposed definitions for grounding relations between qualities and dispositions.
Introduced grounding relations between dispositions and roles.
Applied the framework to model host-pathogen interactions.
Abstract
Ontological representations of qualities, dispositions, and roles have been refined over the past decade, clarifying subtle distinctions in life science research. After articulating a widely-used characterization of these entities within the context of Basic Formal Ontology (BFO), we identify gaps in this treatment and motivate the need for supplementing the BFO characterization. By way of supplement, we propose definitions for grounding relations holding between qualities and dispositions, and dispositions and roles, illustrating our proposal by representing subtle aspects of host-pathogen interactions.
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Taxonomy
TopicsBiomedical Text Mining and Ontologies · Bioinformatics and Genomic Networks · Origins and Evolution of Life
MethodsOntology
