Differentiable Score-Based Likelihoods: Learning CT Motion Compensation From Clean Images
Mareike Thies, Noah Maul, Siyuan Mei, Laura Pfaff, Nastassia, Vysotskaya, Mingxuan Gu, Jonas Utz, Dennis Possart, Lukas Folle, Fabian, Wagner, Andreas Maier

TL;DR
This paper introduces a score-based likelihood model for CT images that enables effective motion artifact correction without requiring prior examples of motion-affected scans, improving robustness and accuracy.
Contribution
The authors develop a novel likelihood-based approach using score models for motion correction in CT, eliminating the need for motion-affected training data.
Findings
Achieves comparable results to state-of-the-art methods
Effectively reduces motion artifacts in CT images
Does not require a dataset of motion-affected samples
Abstract
Motion artifacts can compromise the diagnostic value of computed tomography (CT) images. Motion correction approaches require a per-scan estimation of patient-specific motion patterns. In this work, we train a score-based model to act as a probability density estimator for clean head CT images. Given the trained model, we quantify the deviation of a given motion-affected CT image from the ideal distribution through likelihood computation. We demonstrate that the likelihood can be utilized as a surrogate metric for motion artifact severity in the CT image facilitating the application of an iterative, gradient-based motion compensation algorithm. By optimizing the underlying motion parameters to maximize likelihood, our method effectively reduces motion artifacts, bringing the image closer to the distribution of motion-free scans. Our approach achieves comparable performance to…
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Taxonomy
TopicsMedical Imaging Techniques and Applications · Advanced X-ray and CT Imaging · Radiomics and Machine Learning in Medical Imaging
MethodsSparse Evolutionary Training
