Thermodynamic precision of a chain of motors: the difference between phase and noise correlation

TL;DR

This paper investigates the precision limits of coupled molecular motors modeled as a Kuramoto chain, revealing how noise correlations and coupling affect phase fluctuation precision and dissipation bounds.

Contribution

It introduces a model linking motor noise correlations and coupling to phase fluctuation precision, extending understanding of thermodynamic bounds in motor systems.

Findings

Precision scales with coupling and noise diffusivity.

Spatial noise correlations reduce maximum attainable precision.

Limits of precision are characterized by single-site and center-of-mass behaviors.

Abstract

Inspired by recent experiments on fluctuations of the flagellar beating in sperms and C. reinhardtii, we investigate the precision of phase fluctuations in a system of nearest-neighbour-coupled molecular motors. We model the system as a Kuramoto chain of oscillators with coupling constant $k$ and noisy driving. The precision $p$ is a Fano-factor-like observable which obeys the Thermodynamic Uncertainty Relation (TUR), that is an upper bound related to dissipation. We first consider independent motor noises with diffusivity $D$: in this case the precision goes as $k/D$, coherently with the behavior of spatial order. The minimum observed precision is that of the uncoupled oscillator $p_{unc}$, the maximum observed one is $Np_{unc}$, saturating the TUR bound. Then we consider driving noises which are spatially correlated, as it may happen in the presence of some direct coupling between adjacent motors. Such a spatial correlation in the noise does not reduce evidently the degree of spatial correlation in the chain, but sensibly reduces the maximum attainable precision $p$, coherently with experimental observations. The limiting behaviors of the precision, in the two opposite cases of negligible interaction and strong interaction, are well reproduced by the precision of the single chain site $p_{unc}$ and the precision of the center of mass of the chain $N_{eff} p_{unc}$ with $N_{eff}<N$: both do not depend on the degree of interaction in the chain, but $N_{eff}$ decreases with the correlation length of the motor noises.