DNA-Based Data Storage Systems: A Review of Implementations and Code Constructions
Olgica Milenkovic, Chao Pan

TL;DR
This review explores the development of DNA-based data storage systems, emphasizing implementations, coding strategies, and emerging challenges in molecular data storage and communication.
Contribution
It provides a comprehensive overview of system implementations and introduces new problems and solutions in DNA coding and reconstruction techniques.
Findings
Overview of DNA storage system implementations
Discussion of coding challenges and solutions
Identification of new problems in DNA data communication
Abstract
In this review paper, we delve into the nascent field of molecular data storage, focusing on system implementations and code constructions. We start by providing an overview of basic concepts in synthetic and computational biology. Afterwards, we proceed with a review of the diverse approaches followed to implement such systems. In the process, we identify new problems in communication and coding theory, and discuss some relevant results pertaining to DNA sequence profiles, coded trace reconstruction, coding for DNA punchcard systems and coding for unique reconstruction.
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Taxonomy
TopicsDNA and Biological Computing · Advanced biosensing and bioanalysis techniques · Gene expression and cancer classification
