Sieving and clogging in PEG-PEGDA hydrogel membranes

TL;DR

This study investigates how PEG-PEGDA hydrogel membranes filter latex particles of different sizes, revealing size-dependent permeation influenced by membrane composition and pressure, with nanoscale defects affecting flow.

Contribution

It provides new insights into the mechanisms of particle sieving and clogging in PEG-PEGDA hydrogels, highlighting the role of nanoscale defects and membrane composition.

Findings

20 nm particles permeate depending on composition and pressure

No significant permeation of 100 nm and 1 μm particles

Permeation flux declines due to particle surface layer formation

Abstract

Hydrogels are promising systems for separation applications due to their structural characteristics (i.e. hydrophilicity and porosity). In our study, we investigate the permeation of suspensions of rigid latex particles of different sizes through free-standing hydrogel membranes prepared by photopolymerization of a mixture of poly (ethylene glycol) diacrylate (PEGDA) and large poly (ethylene glycol) (PEG) chains of 300 000 g.mol-1 in the presence of a photoinitiator. Atomic force microscopy (AFM) and cryoscanning electron microscopy (cryoSEM) were employed to characterize the structure of the hydrogel membranes. We find that the 20 nm particle permeation depends on both the PEGDA/PEG composition and the pressure applied during filtration. In contrast, we do not measure a significant permeation of the 100 nm and 1 $\mu$m particles, despite the presence of large cavities of 1 $\mu$m evidenced by cryoSEM images. We suggest that the PEG chains induce local nanoscale defects in the cross-linking of PEGDA-rich walls separating the micron size cavities, that control the permeation of particles and water. Moreover, we discuss the decline of the permeation flux observed in the presence of latex particles, compared to that of pure water. We suggest that a thin layer of particles forms on the surface of the hydrogels.