Conformal folding Dynamics of Amyloid $\beta$-$\tau$ Oligomer in Neuronal Dysfunction

TL;DR

This paper proposes a model for neuronal degeneration driven by amyloid-beta and tau oligomer folding dynamics, aiming to understand disease progression through polymer chain connectivity and simulation.

Contribution

It introduces a novel model linking polymer folding dynamics to neuronal degeneration, with initial development and simulation steps outlined.

Findings

Model development completed

Simulation framework established

Foundation for understanding disease progression

Abstract

In this work, we develop model for neuronal degeneration based on polymer chain folding dynamics and their connectivity in various scale. In the first phase, we just developed the model and numerical simulation need to be complete in order to complete the mathematical development of the disease progression.