Intestinal Microecology in Pediatric Surgery-Related Gastrointestinal Diseases Current Insights and Future Perspectives

TL;DR

This paper reviews how intestinal microecology impacts pediatric gastrointestinal diseases, highlighting its role in disease development, diagnosis, and emerging treatments like microbiota transplantation.

Contribution

It provides a comprehensive overview of the relationship between intestinal microecology and pediatric gastrointestinal diseases, emphasizing new diagnostic and therapeutic approaches.

Findings

Imbalance in microecology is linked to disease development

Microbiota transplantation shows therapeutic potential

Microecological changes can aid in diagnosis

Abstract

Intestinal microecology is established from birth and is constantly changing until homeostasis is reached. Intestinal microecology is involved in the immune inflammatory response of the intestine and regulates the intestinal barrier function. The imbalance of intestinal microecology is closely related to the occurrence and development of digestive system diseases. In some gastrointestinal diseases related to pediatric surgery, intestinal microecology and its metabolites undergo a series of changes, which can provide a certain basis for the diagnosis of diseases. The continuous development of microecological agents and fecal microbiota transplantation technology has provided a new means for its clinical treatment. We review the relationship between pathogenesis, diagnosis and treatment of pediatric surgery-related gastrointestinal diseases and intestinal microecology, in order to provide new ideas and methods for clinical diagnosis, treatment and research.