Comment on "Reproducibility study of Monte Carlo simulations for nanoparticle dose enhancement and biological modeling of cell survival curves" by Velten et al. [Biomed Phys Eng Express 2023;9:045004]
Hans Rabus
TL;DR
This paper critiques a recent study on Monte Carlo simulations for nanoparticle dose enhancement, focusing on methodological issues that may affect the validity of the original findings.
Contribution
It identifies and discusses two key methodological flaws in Velten et al.'s reproducibility study of Monte Carlo simulations.
Findings
Highlights issues in simulation methodology
Questions the reproducibility of the original results
Suggests need for improved simulation protocols
Abstract
This comment highlights two methodological issues with the recent article by Velten et al. [Biomed Phys Eng Express 2023;9:045004]
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Taxonomy
TopicsField-Flow Fractionation Techniques · Statistical Methods in Clinical Trials · Statistical Methods and Inference