SiBBlInGS: Similarity-driven Building-Block Inference using Graphs across States
Noga Mudrik, Gal Mishne, Adam S. Charles

TL;DR
SiBBlInGS is a graph-based framework that infers interpretable building blocks in multi-state time series data, capturing inter- and intra-state variability, and handling missing data, demonstrated on synthetic and real-world datasets.
Contribution
The paper introduces SiBBlInGS, a novel graph-based dictionary learning method that uncovers sparse, interpretable building blocks across states, accounting for variability and missing data.
Findings
Successfully reveals complex patterns in synthetic and real data.
Robust to noise and missing samples in diverse datasets.
Identifies state-specific and invariant components effectively.
Abstract
Time series data across scientific domains are often collected under distinct states (e.g., tasks), wherein latent processes (e.g., biological factors) create complex inter- and intra-state variability. A key approach to capture this complexity is to uncover fundamental interpretable units within the data, Building Blocks (BBs), which modulate their activity and adjust their structure across observations. Existing methods for identifying BBs in multi-way data often overlook inter- vs. intra-state variability, produce uninterpretable components, or do not align with properties of real-world data, such as missing samples and sessions of different duration. Here, we present a framework for Similarity-driven Building Block Inference using Graphs across States (SiBBlInGS). SiBBlInGS offers a graph-based dictionary learning approach for discovering sparse BBs along with their temporal traces,…
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Taxonomy
TopicsFunctional Brain Connectivity Studies · Bioinformatics and Genomic Networks · Mental Health Research Topics
MethodsALIGN
