Large language models improve Alzheimer's disease diagnosis using multi-modality data
Yingjie Feng, Jun Wang, Xianfeng Gu, Xiaoyin Xu, and Min Zhang

TL;DR
This paper demonstrates that integrating large language models with multi-modality data significantly improves Alzheimer's disease diagnosis accuracy, leveraging both imaging and non-imaging patient information.
Contribution
The study introduces a novel approach that combines large language models with multi-modal data, enhancing AI's ability to utilize non-image information for AD diagnosis.
Findings
Achieved state-of-the-art results on the ADNI dataset.
Enhanced model performance by incorporating non-image data.
Showed the effectiveness of LLMs in medical diagnosis tasks.
Abstract
In diagnosing challenging conditions such as Alzheimer's disease (AD), imaging is an important reference. Non-imaging patient data such as patient information, genetic data, medication information, cognitive and memory tests also play a very important role in diagnosis. Effect. However, limited by the ability of artificial intelligence models to mine such information, most of the existing models only use multi-modal image data, and cannot make full use of non-image data. We use a currently very popular pre-trained large language model (LLM) to enhance the model's ability to utilize non-image data, and achieved SOTA results on the ADNI dataset.
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Taxonomy
TopicsTopic Modeling · Interpreting and Communication in Healthcare · Natural Language Processing Techniques
