Reaction-diffusion transport into core-shell geometry: Well-posedness and stability of stationary solutions
T. G. de Jong, G. Prokert, A. E. Sterk

TL;DR
This paper analyzes a reaction-diffusion model with discontinuous coefficients in a core-shell geometry, establishing well-posedness, uniqueness, and stability of stationary solutions using monotone operator theory.
Contribution
It introduces a rigorous mathematical framework for reaction-diffusion equations with discontinuous diffusion coefficients in complex geometries, proving well-posedness and stability.
Findings
Well-posedness of the nonlinear PDE established
Unique and asymptotically stable stationary solutions proven
Application of monotone operator theory to complex geometries
Abstract
We investigate a nonlinear parabolic reaction-diffusion equation describing the oxygen concentration in encapsulated pancreatic cells with a general core-shell geometry. This geometry introduces a discontinuous diffusion coefficient as the material properties of the core and shell differ. We apply monotone operator theory to show well-posedness of the problem in the strong form. Furthermore, the stationary solutions are unique and asymptotically stable. These results rely on the gradient structure of the underlying PDE.
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Taxonomy
TopicsAdvanced Mathematical Modeling in Engineering · Mathematical Biology Tumor Growth · Nonlinear Partial Differential Equations
