Geometric approach for non pharmaceutical interventions in epidemiology
Laurent Evain, Jean-Jacques Loeb

TL;DR
This paper introduces a mathematical, geometrical framework to analyze and optimize non pharmaceutical interventions in epidemiology, distinguishing scientifically driven measures from politically motivated ones, with applications to COVID-19.
Contribution
It presents a novel geometric approach using SIR differential systems to analyze intervention strategies, including resource-based and fixed measures, with insights applicable even with limited real-time data.
Findings
Optimal intervention strategies identified for resource-limited scenarios.
Framework distinguishes scientifically justified measures from political considerations.
Results applicable to real-time decision-making with incomplete data.
Abstract
Various non pharmaceutical interventions have been settled to minimise the burden of the COVID-19 outbreak. We build a framework to analyse the dynamics of non pharmaceutical interventions, to distinguish between mitigations measures leading to objective scientific improvements and mitigations based on both political and scientific considerations. We analyse two possible strategies within this framework. Namely, we consider mitigations driven by the limited resources of the health system and mitigations where a constant set of measures is applied at different moments. We describe the optimal interventions for these scenarios. Our approach is mathematical and involves sir differential systems, it is qualitative and geometrical rather than computational. Along with the analysis of these scenarios, we collect several results that may be useful on their own, in particular on the ground when…
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Taxonomy
TopicsCOVID-19 epidemiological studies · SARS-CoV-2 and COVID-19 Research
MethodsNetwork On Network
