Temperature-dependent magnetic particle imaging with multi-harmonic lock-in detection

TL;DR

This paper introduces a new magnetic particle imaging technique that uses multi-harmonic lock-in detection to improve temperature monitoring accuracy and sensitivity in 3D imaging.

Contribution

The study develops a novel MPI instrument with lock-in detection, enhancing temperature measurement precision and exploring resolution dependence on temperature and harmonic number.

Findings

Lock-in detection reduces noise in temperature measurements.

Resolution varies with temperature and harmonic number.

The method enables more accurate 3D temperature monitoring.

Abstract

Advances in instrumentation and tracer materials are still required to enable sensitive and accurate 3D temperature monitoring by magnetic particle imaging. We have developed a magnetic particle imaging instrument to observe temperature variations using MPI, and discuss resolution dependence on temperature and harmonic number. Furthermore, we present a low noise approach using lock-in detection for temperature measurement, and discuss implications for a new detection modality of MPI.