A Numerical Approach to Sequential Multi-Hypothesis Testing for Bernoulli Model
Andrey Novikov

TL;DR
This paper develops a numerical method for designing optimal sequential multi-hypothesis tests for Bernoulli models, minimizing expected sample size under error constraints, and compares it with existing methods like the matrix SPRT.
Contribution
It introduces a computer-oriented minimization approach using Lagrangian multipliers for sequential testing, applicable to various settings including Bayesian and Kiefer-Weiss, with implementation in R.
Findings
The method effectively designs tests minimizing the Lagrangian function.
Numerical evaluations demonstrate the optimality of the proposed tests.
Comparison shows advantages over traditional matrix SPRT in certain scenarios.
Abstract
In this paper we deal with the problem of sequential testing of multiple hypotheses. The main goal is minimizing the expected sample size (ESS) under restrictions on the error probabilities. We take, as a criterion of minimization, a weighted sum of the ESS's evaluated at some points of interest in the parameter space aiming at its minimization under restrictions on the error probabilities. We use a variant of the method of Lagrange multipliers which is based on the minimization of an auxiliary objective function (called Lagrangian) combining the objective function with the restrictions, taken with some constants called multipliers. Subsequently, the multipliers are used to make the solution comply with the restrictions. We develop a computer-oriented method of minimization of the Lagrangian function, that provides, depending on the specific choice of the parameter points, optimal…
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Taxonomy
TopicsBayesian Modeling and Causal Inference · Statistical Methods in Clinical Trials
