Tracking the Dynamics of the Tear Film Lipid Layer
Tejasvi Kothapalli, Charlie Shou, Jennifer Ding, Jiayun Wang, Andrew, D. Graham, Tatyana Svitova, Stella X. Yu, Meng C. Lin

TL;DR
This paper introduces a computer vision-based method to analyze the tear film lipid layer's dynamics, aiding in the diagnosis of Dry Eye Disease by tracking its spread in videos.
Contribution
It presents a novel tracking algorithm for the tear film lipid layer using computer vision, with the first dataset of videos collected for this purpose.
Findings
Effective tracking of tear film lipid layer spread demonstrated
Method available at https://easytear-dev.github.io/
Potential to improve Dry Eye Disease diagnosis
Abstract
Dry Eye Disease (DED) is one of the most common ocular diseases: over five percent of US adults suffer from DED. Tear film instability is a known factor for DED, and is thought to be regulated in large part by the thin lipid layer that covers and stabilizes the tear film. In order to aid eye related disease diagnosis, this work proposes a novel paradigm in using computer vision techniques to numerically analyze the tear film lipid layer (TFLL) spread. Eleven videos of the tear film lipid layer spread are collected with a micro-interferometer and a subset are annotated. A tracking algorithm relying on various pillar computer vision techniques is developed. Our method can be found at https://easytear-dev.github.io/.
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Taxonomy
TopicsOcular Surface and Contact Lens · Proteoglycans and glycosaminoglycans research · Glaucoma and retinal disorders
