Synthetic Principal Component Design: Fast Covariate Balancing with Synthetic Controls
Yiping Lu, Jiajin Li, Lexing Ying, Jose Blanchet

TL;DR
This paper introduces a novel, efficient optimization algorithm for experimental design using synthetic controls, reducing the problem to phase synchronization and demonstrating superior empirical performance over random designs.
Contribution
It develops a globally convergent algorithm for experimental design via synthetic controls, with the first theoretical guarantees and practical effectiveness demonstrated on real datasets.
Findings
Algorithm surpasses random design in RMSE
Reduces experimental design to phase synchronization
Provides the first global optimality guarantee
Abstract
The optimal design of experiments typically involves solving an NP-hard combinatorial optimization problem. In this paper, we aim to develop a globally convergent and practically efficient optimization algorithm. Specifically, we consider a setting where the pre-treatment outcome data is available and the synthetic control estimator is invoked. The average treatment effect is estimated via the difference between the weighted average outcomes of the treated and control units, where the weights are learned from the observed data. {Under this setting, we surprisingly observed that the optimal experimental design problem could be reduced to a so-called \textit{phase synchronization} problem.} We solve this problem via a normalized variant of the generalized power method with spectral initialization. On the theoretical side, we establish the first global optimality guarantee for experiment…
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Taxonomy
TopicsStatistical Methods and Inference · Advanced Causal Inference Techniques · Statistical Methods in Clinical Trials
