Optimal control related to weak solutions of a chemotaxis-consumption model
Francisco Guill\'en-Gonz\'alez, Andr\'e Luiz Corr\^ea Vianna Filho

TL;DR
This paper investigates an optimal control problem for a chemotaxis-consumption model in three dimensions, establishing existence of optimal controls within a weak solution framework despite potential non-uniqueness of solutions.
Contribution
It proves the existence of optimal controls for a chemotaxis model under weak solution assumptions, addressing challenges of non-uniqueness and bounded controls.
Findings
Existence of optimal control under weak solution framework.
Optimal controls are bounded and satisfy an energy inequality.
Relation to other control problems with non-unique solutions is discussed.
Abstract
In the present work we investigate an optimal control problem related to the following chemotaxis-consumption model in a bounded domain : with , endowed with isolated boundary conditions and initial conditions for , being the cell density, the chemical concentration and the control acting in the -equation through the bilinear term , in a subdomain . We address the existence of optimal control restricted to a weak solution setting, where, in particular, uniqueness of state given a control is not clear. Then by considering weak solutions satisfying an adequate energy inequality, we prove the existence of optimal control subject to uniformly…
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Taxonomy
TopicsMathematical Biology Tumor Growth · Cellular Mechanics and Interactions
