Mindel C. Sheps: Counted, dead or alive
Anders Huitfeldt
TL;DR
This paper discusses Mindel C. Sheps' 1958 innovative approach to selecting effect measures in biostatistics, addressing limitations of relative risk models and connecting to broader scientific theories.
Contribution
It highlights the historical significance and interdisciplinary relevance of Sheps' method, which has been independently rediscovered and aligns with theories in toxicology and philosophy.
Findings
Sheps' approach resolves key issues in effect measure selection.
Her insights are independently rediscovered across disciplines.
The method aligns with theories of mechanism and causality.
Abstract
In the 1958 paper "Shall we count the living or the dead", Canadian physician and biostatistician Mindel C. Sheps proposed a novel approach to choice of effect measure, which resolves key theoretical shortcomings of relative risk models. Sheps' insights have been independently rediscovered multiple times in different academic disciplines, and her approach is consistent with influential work on mechanism of action from toxicology, as well as work on causal generalizability from the psychology and philosophy literature
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Taxonomy
TopicsAdvanced Causal Inference Techniques · Computational Drug Discovery Methods · Statistical Methods in Clinical Trials