Assessment of fiducial motion in CBCT projections of the abdominal tumor using template matching and sequential stereo triangulation

TL;DR

This study evaluates a novel tracking method using template matching and stereo triangulation to assess fiducial motion in CBCT projections for abdominal SBRT, aiming to improve patient setup accuracy and reduce imaging dose.

Contribution

The paper introduces a combined template matching and stereo triangulation algorithm for fiducial tracking in CBCT, enabling accurate motion assessment without additional fluoroscopy.

Findings

Fiducial motion ranges were quantified for pancreas and liver cases.

Predicted couch adjustments closely matched clinical corrections within about 1 mm.

The method effectively assesses fiducial motion, potentially reducing imaging dose.

Abstract

Purpose: To assess the fiducial motion in abdominal stereotactic body radiotherapy (SBRT) using the cone-beam computed tomography (CBCT) projections acquired for pre-treatment patient set-up. Materials and Methods: Pre-treatment CBCT projections and anterior-posterior (AP) and lateral (LAT) pair of fluoroscopic sequences of 7 pancreatic and 6 liver SBRT patients with implanted fiducials were analyzed for 49 treatment fractions retrospectively. A tracking algorithm based on template matching and sequential stereo triangulation algorithms was used to track the fiducials in the CBCT projections and the fluoro sequence pairs. We predicted the clinical couch adjustment from CBCT tracking and compared it with the clinical couch decision made during the patient's treatment. Results: In 3D coordinate, the fiducial motion ranges for pancreas cases were 9.90+/-3.52 mm, 10.65+/-5.91 mm, and 10.74+/-6.24 mm for CBCT, AP, and LAT fluoro, respectively, while in the liver, they were 13.93+/-3.39 mm, 11.17+/-3.75 mm, and 11.52+/-4.33 mm, respectively. Prediction of couch adjustment in LAT, SI, and AP coordinates from CBCT tracking agrees with the actual clinical couch correction within 0.92+/-0.74 mm, 1.37+/-1.26 mm, and 0.68+/-0.56 mm for pancreas cases and within 1.12+/-0.96 mm, 1.15+/-0.92 mm and 0.90+/-0.86 mm for liver cases, respectively. Conclusion: Tracking pre-treatment CBCT projections using template matching and sequential stereo triangulation is suitable for assessing fiducial motion and adjusting the patient setup for abdominal SBRT. CBCT can be used for motion modeling, potentially eliminating the need for additional fluoroscopic pair acquisition and thus reducing the imaging dose to the patient and the total treatment time.