On a multi-dimensional McKean-Vlasov SDE with memorial and singular interaction associated to the parabolic-parabolic Keller-Segel model
Milica Toma\v{s}evi\'c, Guillaume Woessner

TL;DR
This paper establishes the well-posedness of a McKean-Vlasov SDE with singular, memory-dependent interactions in high dimensions, providing a probabilistic interpretation for the Keller-Segel model.
Contribution
It introduces a novel well-posedness result for a McKean-Vlasov SDE with singular, memory-involving interactions and links it to the Keller-Segel system.
Findings
Proved well-posedness of the non-linear martingale problem with singular kernel
Established probabilistic representation for the Keller-Segel system
Derived explicit smallness conditions for model parameters
Abstract
In this work we firstly prove the well-posedness of the non-linear martingale problem related to a McKean-Vlasov stochastic differential equation with singular interaction kernel in for . The particularity of our setting is that the McKean-Vlasov process we study interacts at each time with all its past time marginal laws by means of a singular space-time kernel. Secondly, we prove that our stochastic process is a probabilistic interpretation for the parabolic-parabolic Keller-Segel system in . We thus obtain a well-posedness result to the latter under explicit smallness condition on the parameters of the model.
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Taxonomy
TopicsMathematical Biology Tumor Growth · Markov Chains and Monte Carlo Methods · Gene Regulatory Network Analysis
