A continuous constraint satisfaction problem for the rigidity transition in confluent tissues

TL;DR

This paper introduces an exactly solvable mean field model for the rigidity transition in confluent tissues, mapping it to a continuous constraint satisfaction problem and analyzing the SAT/UNSAT phases and critical behavior.

Contribution

It develops a novel mean field model that maps tissue rigidity to a random continuous constraint satisfaction problem, providing analytical insights into the phase transition.

Findings

Identifies the SAT/UNSAT threshold for the rigidity transition

Characterizes the RSB/ergodicity breaking transition similar to Gardner transition

Compares thermodynamic solutions with numerical minimization results

Abstract

Models of confluent tissues are built out of tessellations of the space (both in two and three dimensions) in which the cost function is constructed in such a way that individual cells try to optimize their volume and surface in order to reach a target shape. At zero temperature, many of these models exhibit a rigidity transition that separates two phases: a liquid phase and a solid (glassy) phase. This phenomenology is now well established but the theoretical understanding is still not complete. In this work we consider an exactly soluble mean field model for the rigidity transition which is based on an abstract mapping. We replace volume and surface functions by random non-linear functions of a large number of degrees of freedom forced to be on a compact phase space. We then seek for a configuration of the degrees of freedom such that these random non-linear functions all attain the same value. This target value is a control parameter and plays the role of the target cell shape in biological tissue models. Therefore we map the microscopic models of cells to a random continuous constraint satisfaction problem (CCSP) with equality constraints. We argue that at zero temperature, the rigidity transition corresponds to the satisfiability transition of the problem. We also characterize both the satisfiable (SAT) and unsatisfiable (UNSAT) phase. In the SAT phase, before reaching the rigidity transition, the zero temperature SAT landscape undergoes an RSB/ergodicity breaking transition of the same type as the Gardner transition in amorphous solids. By solving the RSB equations we compute the SAT/UNSAT threshold and the critical behavior around it. In the UNSAT phase we also compute the average shape index as a function of the target one and we compare the thermodynamical solution of the model with the results of the numerical greedy minimization of the corresponding cost function.