Cost-Efficient Fixed-Width Confidence Intervals for the Difference of Two Bernoulli Proportions
Ignacio Erazo, David Goldsman, Yajun Mei

TL;DR
This paper introduces three cost-efficient fixed-width confidence interval methods for the difference of two Bernoulli proportions, optimizing sampling costs while maintaining coverage and width constraints through simulation-based evaluation.
Contribution
It proposes three novel fixed-width CI construction methods tailored for differing observation costs, demonstrating significant cost savings and efficiency improvements over baseline approaches.
Findings
Up to 50% cost savings with the two-stage procedure
Sequential methods achieve nominal coverage and desired width
Sequential-batching is computationally more efficient
Abstract
We study properties of confidence intervals (CIs) for the difference of two Bernoulli distributions' success parameters, , in the case where the goal is to obtain a CI of a given half-width while minimizing sampling costs when the observation costs may be different between the two distributions. Assuming that we are provided with preliminary estimates of the success parameters, we propose three different methods for constructing fixed-width CIs: (i) a two-stage sampling procedure, (ii) a sequential method that carries out sampling in batches, and (iii) an -stage "look-ahead" procedure. We use Monte Carlo simulation to show that, under diverse success probability and observation cost scenarios, our proposed algorithms obtain significant cost savings versus their baseline counterparts (up to 50\% for the two-stage procedure, up to 15\% for the sequential methods).…
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Taxonomy
TopicsStatistical Methods in Clinical Trials · Advanced Statistical Process Monitoring · Optimal Experimental Design Methods
