Gamma Rhythm Analysis and Simulation Using Neuron Models

TL;DR

This study investigates the interaction between gamma and delta brain rhythms through intracranial recordings in rats, analyzing their correlation and simulating gamma oscillations using neuron models influenced by low-frequency signals.

Contribution

It combines empirical intracranial recordings with neuron model simulations to explore how low-frequency delta rhythms modulate gamma oscillations.

Findings

Delta rhythm modulates gamma rhythm with a small time delay

Low-frequency signals can influence gamma oscillations in neuron models

Simulation results align with empirical correlation analysis

Abstract

Neural oscillations are electrical activities of the brain measurable at different frequencies. This paper studies the interaction between the fast and slow processes in the brain. We recorded signals intracranially from the simple Wistar rats, performed the signal processing, and computed the correlation between envelopes of the high-frequency gamma rhythm and a low-frequency ECoG signal. The analysis shows that the low-frequency signal (delta rhythm) modulates the gamma rhythm with a small time delay. Further, we used simple excitable neuron models, namely FitzHugh-Nagumo and Hindmarsh-Rose, to simulate the gamma rhythm. The low-frequency signal delta rhythm can be used as the input to affect the threshold and simulate gamma rhythm using these neuron models.