Effects of self-avoidance on the packing of stiff rods on ellipsoids

TL;DR

This paper uses a statistical-mechanics model to analyze how geometry and self-avoidance influence the packing and ordering of stiff filaments inside ellipsoidal containers, revealing phase transitions and mechanical properties.

Contribution

It provides an analytical framework linking container shape, self-avoidance, and filament ordering, including a phase transition analysis and comparison to purely mechanical models.

Findings

Self-avoidance significantly influences filament orientation.

First-order transition from azimuthal to polar order in oblate cells.

Critical behavior related to butterfly catastrophe model.

Abstract

Using a statistical-mechanics approach, we study the effects of geometry and self-avoidance on the ordering of slender filaments inside non-isotropic containers, considering cortical microtubules in plant cells, and packing of genetic material inside viral capsids as concrete examples. Within a mean-field approximation, we show analytically how the shape of the container, together with self-avoidance, affects the ordering of the stiff rods. We find that the strength of the self-avoiding interaction plays a significant role in the preferred packing orientation, leading to a first-order transition for oblate cells, where the preferred orientation changes from azimuthal, along the equator, to a polar one, when self-avoidance is strong enough. While for prolate spheroids the ground state is always a polar-like order, strong self-avoidance results with a deep meta-stable state along the equator. We compute the critical surface describing the transition between azimuthal and polar ordering in the three dimensional parameter space (persistence length, eccentricity, and self-avoidance) and show that the critical behavior of this system is in fact related to the butterfly catastrophe model. We calculate the pressure and shear stress applied by the filament on the surface, and the injection force needed to be applied on the filament in order to insert it into the volume. We compare these results to the pure mechanical study where self-avoidance is ignored, and discuss similarities and differences.