Familial inference: tests for hypotheses on a family of centres
Ryan Thompson, Catherine S. Forbes, Steven N. MacEachern, Mario, Peruggia

TL;DR
This paper introduces a Bayesian nonparametric method to test hypotheses on a family of centres, addressing the gap between scientific hypotheses and statistical tests that assume a single centre, with theoretical and practical validation.
Contribution
It proposes a novel approach for testing a family of plausible centres, such as the Huber family, using a new pathwise optimization routine and Bayesian methods.
Findings
The new test has favorable theoretical properties.
Experimental validation demonstrates effectiveness.
Case studies show practical applicability.
Abstract
Statistical hypotheses are translations of scientific hypotheses into statements about one or more distributions, often concerning their centre. Tests that assess statistical hypotheses of centre implicitly assume a specific centre, e.g., the mean or median. Yet, scientific hypotheses do not always specify a particular centre. This ambiguity leaves the possibility for a gap between scientific theory and statistical practice that can lead to rejection of a true null. In the face of replicability crises in many scientific disciplines, significant results of this kind are concerning. Rather than testing a single centre, this paper proposes testing a family of plausible centres, such as that induced by the Huber loss function (the Huber family). Each centre in the family generates a testing problem, and the resulting family of hypotheses constitutes a familial hypothesis. A Bayesian…
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Taxonomy
TopicsBayesian Methods and Mixture Models · Statistical Methods and Bayesian Inference · Gene expression and cancer classification
