Accumulation time of diffusion in a 3D singularly perturbed domain

TL;DR

This paper extends the analysis of diffusion accumulation time from 2D to 3D singularly perturbed domains, developing new asymptotic methods to handle the increased mathematical complexity.

Contribution

The paper introduces a novel asymptotic framework for calculating accumulation time in 3D diffusion problems with small holes, building on previous 2D methods.

Findings

Derived asymptotic expansion of accumulation time in 3D domains

Identified and addressed s-singularities in Laplace space solutions

Extended matched asymptotics and Green's function techniques to 3D

Abstract

Boundary value problems for diffusion in singularly perturbed domains (domains with small holes removed from the interior) is a topic of considerable current interest. Applications include intracellular diffusive transport and the spread of pollutants or heat from localized sources. In a previous paper, we introduced a new method for characterizing the approach to steady-state in the case of two-dimensional (2D) diffusion. This was based on a local measure of the relaxation rate known as the accumulation time $T(\x)$. The latter was calculated by solving the diffusion equation in Laplace space using a combination of matched asymptotics and Green's function methods. We thus obtained an asymptotic expansion of $T(\x)$ in powers of $\nu=-1/\ln \epsilon$, where $\epsilon$ specifies the relative size of the holes. In this paper, we develop the corresponding theory for three-dimensional (3D) diffusion. The analysis is a non-trivial extension of the 2D case due to differences in the singular nature of the Laplace transformed Green's function. In particular, the asymptotic expansion of the solution of the 3D diffusion equation in Laplace space involves terms of order $O((\epsilon/s)^n)$, where $s$ is the Laplace variable. These $s$-singularities have to be removed by partial series resummations in order to obtain an asymptotic expansion of $T(\x)$ in powers of $\epsilon$.