The hyperbolic-parabolic chemotaxis system for vasculogenesis: global dynamics and relaxation limit toward a Keller-Segel model
Timoth\'ee Crin-Barat, Qingyou He, Ling-Yun Shou

TL;DR
This paper analyzes a hyperbolic-parabolic chemotaxis system modeling vasculogenesis, establishing global well-posedness, decay rates, and rigorously justifying the relaxation limit toward the Keller-Segel model.
Contribution
It provides the first rigorous analysis of the global dynamics and relaxation limit for this hyperbolic-parabolic chemotaxis system in critical regularity spaces.
Findings
Global classical solutions exist for small initial data.
Optimal decay rates of solutions are established.
The relaxation limit converges to Keller-Segel equations with explicit rate.
Abstract
An Euler-type hyperbolic-parabolic system of chemotactic aggregation describing the vascular network formation is investigated in the critical regularity setting. For small initial data around a constant equilibrium state, the well-posedness of the global classical solution to the Cauchy problem with general pressure laws is established in homogeneous hybrid Besov spaces. Then, the optimal time-decay rates of the global solution are analyzed under an additional regularity assumption on the initial data. Furthermore, the relaxation limit (large friction limit) of the hyperbolic-parabolic system is justified rigorously. It is shown that as the friction coefficient tends to zero, the global solution of the hyperbolic-parabolic chemotaxis system converges to the global solution of the Keller-Segel equations with an explicit convergence rate. To capture the dissipative properties of the…
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMathematical Biology Tumor Growth
