Nonlinear random walks optimize the trade-off between cost and prevention in epidemics lockdown measures : the ESIR model

TL;DR

This paper introduces the ESIR model, a nonlinear random walk approach on metapopulation networks that optimizes epidemic containment while minimizing social and economic costs through targeted social distancing.

Contribution

The paper presents a novel ESIR model based on nonlinear random walks with capacity constraints, enabling effective epidemic control with minimized mobility impact.

Findings

Model reduces disease spread effectively.

Approaches Pareto optimality in mobility and health outcomes.

Validated on empirical transport networks.

Abstract

Contagious diseases can spread quickly in human populations, either through airborne transmission or if some other spreading vectors are abundantly accessible. They can be particularly devastating if the impact on individuals' health has severe consequences on the number of hospitalizations or even deaths. Common countermeasures to contain the epidemic spread include introducing restrictions on human interactions or their mobility in general which are often associated with an economic and social cost. In this paper, we present a targeted model of optimal social distancing on metapopulation networks, named ESIR model, which can effectively reduce the disease spreading and at the same time minimize the impact on human mobility and related costs. The proposed model is grounded in a nonlinear random walk process that considers the finite carrying capacity of the network's metanodes, the physical patches where individuals interact within mobility networks. This later constrain is modeled as a slack compartment E for the classic SIR model and quantifies the density of vacant spaces to accommodate the diffusing individuals. Formulating the problem as a multi-objective optimization problem shows that when the walkers avoid crowded nodes, the system can rapidly approach Pareto optimality, thus reducing the spreading considerably while minimzing the impact on human mobility as also validated in empirical transport networks. These results envisage ad hoc mobility protocols that can potentially enhance policy making for pandemic control.